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Catalog No: OASE00276-HRP
Size:100ug
Price: $429.00
SKU
OASE00276-HRP
Availability: Domestic: within 3-5 days delivery | International: 3-5 days
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Brevican Antibody : HRP (OASE00276-HRP)

Datasheets/ManualsPrintable datasheet for OASE00276-HRP
Product Info
Predicted Species ReactivityMouse, Rat
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityMonoclonal
CloneS294A-6
IsotypeIgG2B
HostMouse
ConjugationHRP: Horseradish Peroxidase
ApplicationICC, WB
Additional InformationBackground Info: Detects ~140kDa (and smaller due to proteolytic cleavage)
::Scientific Background: Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult
brain. It is a member of the lectican family of
aggregating extracellular matrix proteoglycans that bear
chondroitin sulfate (CS) chains. It is highly expressed in
the central nervous system and is thought to stabilize
synapses and inhibit neural plasticity. Brevican is
secreted from astrocytes and neurons as a 145 kD core
protein that bears up to three, covalently-linked, CS
chains. It is also is secreted as a 145 kD core protein
without CS chains. When cleaved by extracellular
glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
::Certificate of Analysis: 1 ug/mL was sufficient for detection of Brevican in 20ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenFusion protein amino acids 219-655 of rat Brevican,
accession number P55068.
PurificationProtein G Purified
Concentration0.6-0.7 mg/ml
Dilution1:1000 WB
Storage BufferPBS pH7.4, 50% glycerol
Reference1. Yamada H., Watanabe K., Shimonaka M. and Yamaguchi Y. (1994) J. Biol. Chem. 269: 10119-10126.
2. Yamada H., Watanabe K., Shimonaka M., Yamasaki M.
and Yamaguchi Y. (1995) Biochem. Biophys. Res.
Commun. 216: 957-963.
3. Rauch U., et al. (1997) Genomics 44: 15-21.
4. Zhang H., Kelly G., Zerillo C., Jaworski D.M. and
Hockfield S. (1998) J. Neurosci. 7: 2370-2376.
5. Aspberg A., Adam S., Kostka G., Timpl R. and
Heinegard D. (1999) J. Biol. Chem. 274: 20444-20449.
Gene SymbolBcan
Gene Full Namebrevican
Alias SymbolsBEHAB, ALPBRE
NCBI Gene Id25393
Uniprot IDP55068
Protein Accession #NP_001028837.1
  1. What is the species homology for "Brevican Antibody : HRP (OASE00276-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat".

  2. How long will it take to receive "Brevican Antibody : HRP (OASE00276-HRP)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Brevican Antibody : HRP (OASE00276-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Brevican Antibody : HRP (OASE00276-HRP)"?

    This target may also be called "BEHAB, ALPBRE" in publications.

  5. What is the shipping cost for "Brevican Antibody : HRP (OASE00276-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Brevican Antibody : HRP (OASE00276-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Brevican Antibody : HRP (OASE00276-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Brevican Antibody : HRP (OASE00276-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BCAN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BCAN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BCAN"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BCAN"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BCAN"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BCAN"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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