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BRD4 Antibody - C-terminal region : FITC (ARP39076_P050-FITC)

100 ul
$319.00
In Stock
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Conjugation Options

ARP39076_P050 Unconjugated

ARP39076_P050-HRP Conjugated

ARP39076_P050-Biotin Conjugated

Gene Symbol:
BRD4
Official Gene Full Name:
Bromodomain containing 4
NCBI Gene Id:
23476
Protein Name:
Bromodomain-containing protein 4
Swissprot Id:
O60885-2
Protein Accession #:
NP_055114
Nucleotide Accession #:
NM_014299
Alias Symbols:
CAP, HUNKI, MCAP, HUNK1
Replacement Item:
This antibody may replace item sc-141740 from Santa Cruz Biotechnology.
Description of Target:
BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Protein Size (# AA):
722
Molecular Weight:
80kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
CHIP, IF, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BRD4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BRD4.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human BRD4
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-BRD4 (ARP39076_P050)
Peptide Sequence:
Synthetic peptide located within the following region: EIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
1 mg/ml
Protein Interactions:
AFF1; CDK9; CCNT1; STAT3; JMJD6; TCERG1; HEXIM1; RN7SK; PRPF40A; vif; RPL6; MYC; MLLT1; ELAVL1; SUMO2; UBC; YWHAZ; KAT8; C8orf33; MESDC2; HIST1H4A; HIST1H3A; YWHAE; MED1; EP300; KDM5B; C7orf25; CHFR; CLDN1; RFC1; RFC4; HIST2H3C; HIST2H4A; MED12; MED24; ME
Blocking Peptide:
For anti-BRD4 (ARP39076_P050-FITC) antibody is Catalog # AAP39076 (Previous Catalog # AAPS05411)
Datasheets/Manuals:
Printable datasheet for anti-BRD4 (ARP39076_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm
Target Reference:
Schweiger,M.R., (2006) J. Virol. 80 (9), 4276-4285

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