Catalog No: OAGA08728
Size:100 ul
Price: $372.00
SKU
OAGA08728
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAGA08728
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityMonoclonal
Clone5F6
IsotypeIgG1
HostMouse
ApplicationIHC, IHC-F, IHC-P, WB
Reconstitution and StorageKeep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
ImmunogenAmino acids 2336-2478 of human BRCA2 expressed in E. coli. BRCA2-P400.
PurificationProtein G purified
Concentration1 mg/ml
Application InfoDo not boil samples for longer than two minutes. For WB: Use at a concentration of 1-5 ug/ml. Predicted molecular weight: 380 kDa. Optimal dilutions/concentrations should be determined by the reseracher.
Storage BufferPhosphate-buffered saline, pH 7.2, no preservative added.
Gene SymbolBRCA2
Gene Full NameBRCA2, DNA repair associated
Alias SymbolsFAD, FACD, FAD1, GLM3, BRCC2, FANCD, PNCA2, FANCD1, XRCC11, BROVCA2
NCBI Gene Id675
Protein Namebreast cancer type 2 susceptibility protein
Description of TargetInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
Uniprot IDP51587
Protein Accession #NP_000050.2
Nucleotide Accession #NM_000059.3
  1. What is the species homology for "BRCA2 Antibody (OAGA08728)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "BRCA2 Antibody (OAGA08728)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "BRCA2 Antibody (OAGA08728)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BRCA2 Antibody (OAGA08728)"?

    This target may also be called "FAD, FACD, FAD1, GLM3, BRCC2, FANCD, PNCA2, FANCD1, XRCC11, BROVCA2" in publications.

  5. What is the shipping cost for "BRCA2 Antibody (OAGA08728)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BRCA2 Antibody (OAGA08728)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BRCA2 Antibody (OAGA08728)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BRCA2 Antibody (OAGA08728)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BRCA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BRCA2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BRCA2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BRCA2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BRCA2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BRCA2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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