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Catalog No: OAAB18600
Size:400ul
Price: $463.00
SKU
OAAB18600
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB18600
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeRabbit Ig
HostRabbit
ApplicationICC, IF
::Function: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.
Cellular Location: Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.
Tissue Location: Brain and testis.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis BRAF antibody is generated from rabbits immunized with BRAF recombinant protein.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration0.5 mg/ml
Application InfoWB: 1:1000
FC: 1:10~50
ReferenceHingorani, S.R., et al., Cancer Res. 63(17):5198-5202 (2003).
Lee, J.W., et al., Br. J. Cancer 89(10):1958-1960 (2003).
Davies, H., et al., Nature 417(6892):949-954 (2002).
Naoki, K., et al., Cancer Res. 62(23):7001-7003 (2002).
Stephens, R.M., et al., Mol. Cell. Biol. 12(9):3733-3742 (1992).
Gene SymbolBRAF
Alias SymbolsNS7, B-raf, BRAF1, RAFB1, B-RAF1
NCBI Gene Id673
Description of TargetBRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
Uniprot IDP15056
Protein Accession #NP_004324.2
Molecular Weight84 kDa
  1. What is the species homology for "BRAF Antibody (OAAB18600)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "BRAF Antibody (OAAB18600)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "BRAF Antibody (OAAB18600)" provided in?

    This item is provided in "Liquid PBS with 0.09% (W/V) sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BRAF Antibody (OAAB18600)"?

    This target may also be called "NS7, B-raf, BRAF1, RAFB1, B-RAF1" in publications.

  5. What is the shipping cost for "BRAF Antibody (OAAB18600)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BRAF Antibody (OAAB18600)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BRAF Antibody (OAAB18600)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "84 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BRAF Antibody (OAAB18600)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BRAF"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BRAF"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BRAF"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BRAF"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BRAF"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BRAF"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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