Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: OAPB00112 (Formerly GWB-8623DA)
Size:100UG
Price: $461.00
SKU
OAPB00112
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for BNIP3L Antibody (OAPB00112) (OAPB00112)
Product Info
Predicted Species ReactivityBovine|Human|Mouse
Product FormatLiquid. Bnip3L Antibody is supplied in PBS containing 0.02% sodium azide.
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
::Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and Storage2°C to 8°C
ImmunogenBnip3L antibody was raised against a 16 amino acid peptide near the center of human Bnip3L. The immunogen is located within amino acids 60 - 110 of Bnip3L.
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman
Concentration1 mg/ml
Blocking PeptideFor anti-BNIP3L (OAPB00112) antibody is Catalog # OEPB02232
Application InfoBnip3L antibody can be used for detection of Bnip3L by Western blot at 0.5 to 1 ug/ml. The approximate 40 kDa top band represents monomer of Bnip3L (4). It is human and mouse reactive. (Optimal dilution should be determined by user)
ReferenceMatsushima M, Fujiwara T, Takahashi E, et al. Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3. Genes Chromosomes Cancer 1998;21:230-5 ;Yasuda M, Han JW, Dionne CA, Boyd JM, Chinnadurai G. BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3. Cancer Res 1999;59:533-7 ;Chen G, Cizeau J, Vande Velde C, et al. Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. J Biol Chem 1999;274(1):7-10 ;Imazu T, Shimizu S, Tagami S, et al. Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability. Oncogene. 1999;18:4523-9 (RD1200)
Gene SymbolBNIP3L
Gene Full NameBCL2 interacting protein 3 like
Alias Symbolsadenovirus E1B19k-binding protein B5;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like;BCL2/adenovirus E1B 19-kd protein-interacting protein 3a;BCL2/adenovirus E1B 19kDa interacting protein 3 like;BNIP3a;NIP3L;NIP3-like protein X;NIP-3-like protein X;NIX.
NCBI Gene Id665
Protein NameBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like|BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform 1 [Homo sapiens]
Description of TargetInduces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Uniprot IDO60238
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/NP_004322
Nucleotide Accession #NM_004331.2; XM_005273617.2
Molecular WeightPredicted: 24 kDa Observed: 36, 40 kDa
  1. What is the species homology for "BNIP3L Antibody (OAPB00112)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Human|Mouse".

  2. How long will it take to receive "BNIP3L Antibody (OAPB00112)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "BNIP3L Antibody (OAPB00112)" provided in?

    This item is provided in "Liquid. Bnip3L Antibody is supplied in PBS containing 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BNIP3L Antibody (OAPB00112)"?

    This target may also be called "adenovirus E1B19k-binding protein B5;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like;BCL2/adenovirus E1B 19-kd protein-interacting protein 3a;BCL2/adenovirus E1B 19kDa interacting protein 3 like;BNIP3a;NIP3L;NIP3-like protein X;NIP-3-like protein X;NIX." in publications.

  5. What is the shipping cost for "BNIP3L Antibody (OAPB00112)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BNIP3L Antibody (OAPB00112)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BNIP3L Antibody (OAPB00112)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "Predicted: 24 kDa Observed: 36, 40 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BNIP3L Antibody (OAPB00112)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BNIP3L"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BNIP3L"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BNIP3L"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BNIP3L"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BNIP3L"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BNIP3L"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:BNIP3L Antibody (OAPB00112)
Your Rating
We found other products you might like!