Aviva Systems Biology will be closed in observance of Good Friday 3/29/2024. If you are in need of any assistance please email info@avivasysbio.com

Catalog No: OAAB15457
Size:400UL
Price: $396.00
SKU
OAAB15457
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for BMPR1A Antibody (N-term) (OAAB15457)
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid.PBS with 0.09% (W/V) sodium azide
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationFlow cytometry, Western blot
Additional InformationFunction: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Cellular Location: Cell membrane; Single-pass type I membrane protein.Cell surface.
Tissue Location: Highly expressed in skeletal muscle.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis BMPR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BMPR1A.
PurificationThis antibody is purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Predicted Homology Based on Immunogen SequenceHuman; Mouse
Concentration2 mg/ml
Application InfoWB: 1:1,000
FC: 1:10~50
Optimal dilutions should be determined by the end user.
ReferenceWaite, K.A., et al., Hum. Mol. Genet. 12(6):679-684 (2003).
Zhou, X.P., et al., Am. J. Hum. Genet. 69(4):704-711 (2001).
Astrom, A.K., et al., Mamm. Genome 10(3):299-302 (1999).
ten Dijke, P., et al., Oncogene 8(10):2879-2887 (1993).
Ide, H., et al., Cytogenet. Cell Genet. 81 (3-4), 285-286 (1998)
Gene SymbolBMPR1A
Gene Full Namebone morphogenetic protein receptor type 1A
Alias Symbols10q23del;activin A receptor, type II-like kinase 3;activin receptor-like kinase 3;ACVRLK3;ALK3;ALK-3;BMP type-1A receptor;BMPR-1A;bone morphogenetic protein receptor type-1A;bone morphogenetic protein receptor, type IA;CD292;serine/threonine-protein kinase receptor R5;SKR5.
NCBI Gene Id657
Protein NameNP_004320.2, P36894
Description of TargetBone morphogenetic protein receptor type-1A, bone morphogenetic protein receptor type-1A precursor [Homo sapiens]
Uniprot IDhttps://www.uniprot.org/uniprot/P36894
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/NP_004320.2
Molecular Weight60198
  1. What is the species homology for "BMPR1A Antibody - N-terminal region (OAAB15457)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "BMPR1A Antibody - N-terminal region (OAAB15457)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks ".

  3. What buffer format is "BMPR1A Antibody - N-terminal region (OAAB15457)" provided in?

    This item is provided in "Liquid.PBS with 0.09% (W/V) sodium azide".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BMPR1A Antibody - N-terminal region (OAAB15457)"?

    This target may also be called "10q23del;activin A receptor, type II-like kinase 3;activin receptor-like kinase 3;ACVRLK3;ALK3;ALK-3;BMP type-1A receptor;BMPR-1A;bone morphogenetic protein receptor type-1A;bone morphogenetic protein receptor, type IA;CD292;serine/threonine-protein kinase receptor R5;SKR5." in publications.

  5. What is the shipping cost for "BMPR1A Antibody - N-terminal region (OAAB15457)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BMPR1A Antibody - N-terminal region (OAAB15457)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BMPR1A Antibody - N-terminal region (OAAB15457)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "60198".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BMPR1A Antibody - N-terminal region (OAAB15457)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BMPR1A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BMPR1A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BMPR1A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BMPR1A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BMPR1A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BMPR1A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:BMPR1A Antibody - N-terminal region (OAAB15457)
Your Rating
We found other products you might like!