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BMP7 Antibody (OASA07474)

50 ug
$395.00
In Stock
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Gene Symbol:
BMP7
NCBI Gene Id:
655
Protein Name:
Bone morphogenetic protein 7
Swissprot Id:
P18075
Protein Accession #:
NP_001710.1
Alias Symbols:
OP-1, BMP7
Replacement Item:
This antibody may replace item sc-34766 from Santa Cruz Biotechnology.
Description of Target:
RABBIT ANTI HUMAN BMP-7
Protein Size (# AA):
431
Host:
Rabbit
Clonality:
Polyclonal
Application:
ELISA, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BMP7.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BMP7.
Immunogen:
The immunogen for anti-BMP7 antibody: recombinant human BMP-7
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Datasheets/Manuals:
Printable datasheet for anti-BMP7 antibody - OASA07474
Specificity:
BMP-7
Isotype:
Polyclonal IgG
Application Info:
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
:::
Preservative Stabilisers: 0.09% - Sodium Azide
Antiserum Preparation: Antisera to human BMP-7 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
:::
Approx Protein Conc: IgG concentration 1.0 mg/ml
Buffer Solutions: Phosphate buffered saline pH7.4
Target Reference:
1. Balemans, W. and Van Hul, W. (2002) Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev. Biol. 250: 231-250.
2. Sebald, W. et al. (2004) Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction. Biol. Chem. 385: 697-710.
3. Wang, Shi-Nong et al. (2001) Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy. J. Am. Soc. Nephrol. 12: 2392-2399.
4. Godin, R.E. et al. (1998) Regulation of BMP7 expression during kidney development. Development 125: 3473-3482.
5. Trousse, F. et al. (2001) BMP4 mediates apoptotic cell death in the developing chick eye. J. Neuroscience 21: 1292-1301.

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