BMP4 Antibody - C-terminal region (ARP63062_P050)

Catalog No: ARP63062_P050

25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
• Peptide Sequence: Synthetic peptide located within the following region: NWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-BMP4 (ARP63062_P050) antibody is Catalog # AAP63062
• Enhanced Validation:

  Relative Expression (Western Blot)

• Publications:

  Ganti, R., Hunt, R. C., Parapuram, S. K. & Hunt, D. M. Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 48, 1853-63 (2007). 17389521

Target Info

• Gene Symbol: BMP4
• Gene Full Name: Bone morphogenetic protein 4
• Alias Symbols: ZYME, BMP2B, OFC11, BMP2B1, MCOPS6
• NCBI Gene Id: 652
• Protein Name: Bone morphogenetic protein 4
• Description of Target: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
• Uniprot ID: P12644
• Protein Accession #: NP_001193
• Nucleotide Accession #: NM_001202
• Protein Size (# AA): 408
• Molecular Weight: 40 kDa
• Protein Interactions: BMPR2; ZFYVE9; UBC; BGN; GREM2; BMPER; SOSTDC1; CHRDL2; STAP2; BMPR1B; NOG; BMP8B; HTRA1; BMPR1A; CHRDL1; BMP4; TWSG1; CHRD;