BMP4 Antibody : Biotin (OABF00667-Biotin)

Catalog No: OABF00667-Biotin

Size:100ul

Product Info

• Predicted Species Reactivity: Mouse, Rat
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Biotin
• Application: WB, IHC-P, IF
• Additional Information: Subcellular location:
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: KLH conjugated synthetic peptide derived from rat BMP4
• Purification: Purified by Protein A.
• Concentration: 1 mg/ml
• Application Info: WB(1:100-1000)
  IHC-P(1:100-500)
  IF(1:50-200)

Target Info

• Alias Symbols: BMP 4, BMP2B, BMP2B1, Bone morphogenetic protein 4, DVR4, ZYME, BMP4_HUMAN, BMP-4, Bone morphogenetic protein 2B, BMP-2B.
• Description of Target: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.