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Catalog No: OPCD01669
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OPCD01669
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Datasheets/ManualsPrintable datasheet for BMP2 Recombinant Protein (OPCD01669)
Product Info
Predicted Species ReactivityRat|Rattus norvegicus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ser49-Ile243
::Subcellular Location: Secreted
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolBmp2
Gene Full Namebone morphogenetic protein 2
Alias SymbolsBMP-2;BMP-2A;bone morphogenetic protein 2;bone morphogenetic protein 2A.
NCBI Gene Id29373
Protein NameBone morphogenetic protein 2
Description of TargetInduces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A-ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.
Uniprot IDP49001
Protein Accession #NP_058874.1
Nucleotide Accession #NM_017178.1
Protein Size (# AA)Ser49~Ile243
Molecular Weight26kDa
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