Catalog No: OPCD01664
Price: $0.00
SKU
OPCD01664
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/Manuals | Printable datasheet for BMP2 Recombinant Protein (OPCD01664) |
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Predicted Species Reactivity | Homo sapiens|Human |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) Residues: Gln283-Arg396 Subcellular Location: Secreted Isoelectric Point: 7.3 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 97% |
Source | E.coli |
Tag | N-terminal His and GST Tag |
Gene Symbol | BMP2 |
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Gene Full Name | bone morphogenetic protein 2 |
Alias Symbols | BDA2;BMP2A;bone morphogenetic protein 2;bone morphogenetic protein 2A;SSFSC;SSFSC1. |
NCBI Gene Id | 650 |
Protein Name | Bone morphogenetic protein 2 |
Description of Target | Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). |
Uniprot ID | P12643 |
Protein Accession # | NP_001191.1 |
Nucleotide Accession # | NM_001200.3 |
Protein Size (# AA) | Gln283~Arg396 |
Molecular Weight | 43kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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