- NCBI Gene Id:
- Protein Name:
- Bone morphogenetic protein 2
- Alias Symbols:
- BMP2A, BMP2
- Replacement Item:
- This antibody may replace item sc-128103 from Santa Cruz Biotechnology.
- Description of Target:
- RABBIT ANTI HUMAN BMP-2
- Protein Size (# AA):
- ELISA, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express BMP2.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express BMP2.
- The immunogen for anti-BMP2 antibody: recombinant human BMP-2.
- Predicted Species Reactivity:
- Predicted Homology Based on Immunogen Sequence:
- Product Format:
- Purified IgG - liquid
- Reconstitution and Storage:
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Printable datasheet for anti-BMP2 antibody - OASA07470
- Polyclonal IgG
- Application Info:
- Dilution: 0.25 ug/ml. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
- Preservative Stabilisers: 0.09% - Sodium Azide (NaN3)
Antiserum Preparation: Antisera to human BMP-2 were raised by repeated immunisations of rabbits with highly purified antigen.
- Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline pH7.4.
- Target Reference:
- 1. Balemans, W. and Van Hul, W. (2002) Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev. Biol. 250: 231-250.
2. Sebald, W. et al. (2004) Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction. Biol. Chem. 385: 697-710.
3. Keller, S. et al. (2004) Molecular recognition of BMP-2 and BMP receptor IA. Nature Structural and Molecular Biology. 11: 481-488.
4. Kirsch, T. et al. (2000) BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II. EMBO J. 19: 3314-3324.
5. Kimura, N. et al. (2000) BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6. J. Biol. Chem. 275: 17647-17652.
- Tips Information: