BMP 7 Protein (OPPA00596)

Catalog No: OPPA00596 (Formerly GWB-AB005C)

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: BMP-7 was lyophilized from a concentrated (1mg/ml) sterile solution containing 10mM sodium citrate pH=3.5. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Host: E. Coli
• Application: WB, ELISA, SDS-PAGE
• Additional Information: Solubility: It is recommended to reconstitute the lyophilized Bone Morphogenetic Protein-7 in sterile 20mM-100mM AcOH (acetic Acid) not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
  Product Introduction: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
  Product Description: Bone Morphogenetic Protein-7 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain containing 139 amino acids and having a molecular mass of 15679.97 Dalton. The BMP-7 is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Lyophilized BMP-7 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution BMP 7 Human should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Peptide Sequence: The sequence of the first five N - terminal amino acids was determined and was found to be Ser - Thr - Gly - Ser - Lys.
• Application Info: 1. Molecular standard (Western, ELISA) in studying secreted BMP-7.
  2. Preparing antibodies for BMP-7 monomer.
  3. Molecule standard in detecting secreted BMP-7 in reduced SDS-PAGE.

Target Info

• Gene Symbol: BMP 7
• Alias Symbols: OP-1
• NCBI Gene Id: 655
• Protein Name: Bone morphogenetic protein 7
• Description of Target: Recombinant Human Bone Morphogenetic protein-7
• Uniprot ID: P18075
• Protein Accession #: NP_001710.1
• Protein Size (# AA): Recombinant