BMP 4 Protein (OPPA00624)

Catalog No: OPPA00624 (Formerly GWB-21F5A4)

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: BMP-4 was lyophilized from a concentrated (1mg/ml) solution containing no additives. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Host: E. Coli
• Application: WB, ELISA, SDS-PAGE
• Additional Information: Solubility: It is recommended to reconstitute the lyophilized Bone Morphogenetic Protein-4 in sterile 20mM AcOH (acetic Acid) not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
  Product Introduction: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
  Product Description: Bone Morphogenetic Protein-4 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, Polypeptide chain containing 116 amino acids and having a molecular mass of 13009 Dalton. The BMP-4 is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Lyophilized Bone Morphogenetic Protein-4 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution BMP4 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Peptide Sequence: SPKHHSQRAR KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR.
• Application Info: 1. Molecular standard (Western, ELISA) in studying secreted BMP-4.
  2. Preparing antibodies for BMP-4 monomer.
  3. Molecule standard in detecting secreted BMP-4 in reduced SDS-PAGE.

Target Info

• Gene Symbol: BMP 4
• Alias Symbols: ZYME, BMP2B, OFC11, BMP2B1, MCOPS6
• NCBI Gene Id: 652
• Protein Name: Bone morphogenetic protein 4
• Description of Target: Recombinant Human Bone Morphogenetic protein-4
• Uniprot ID: P12644
• Protein Accession #: NP_001193.2
• Protein Size (# AA): Recombinant