BLNK Antibody - middle region (ARP46185_P050)

Catalog No: ARP46185_P050

WB Suggested Anti-BLNK Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: NCI-H226 cell lysate

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BLNK
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: QYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKV
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-BLNK (ARP46185_P050) antibody is Catalog # AAP46185 (Previous Catalog # AAPP27022)
• Reference: Rock,J., (2007) Eur. J. Immunol. 37 (12), 3564-3575

Target Info

• Gene Symbol: BLNK
• Gene Full Name: B-cell linker
• Alias Symbols: bca, AGM4, BASH, LY57, SLP65, BLNK-S, SLP-65
• NCBI Gene Id: 29760
• Protein Name: B-cell linker protein
• Description of Target: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological function
• Uniprot ID: Q8WV28
• Protein Accession #: NP_037446
• Nucleotide Accession #: NM_013314
• Protein Size (# AA): 456
• Molecular Weight: 50kDa
• Protein Interactions: ERBB2; BTK; GRAP2; SYK; PLCG1; CBL; AIFM1; NCK2; TLN1; MAP2K4; PPP2R2C; PLCG2; MYBPC3; LYN; HSPA4; GRB2; CD79A; CAPZB; CAPZA2; CAPZA1; CLEC17A; WDR81; DOK3; SH3KBP1; CD2AP; HSPH1; VAV3; CMTM3; CBLB; CRKL; MAP4K1; LCP2; NCK1; ITK; PTPN6; VAV1; CD72;