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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for BLM Antibody (OAAF00937) |
|---|
| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin |
| Reconstitution and Storage | -20°C |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Bloom Syndrome. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Specificity | Bloom Syndrome antibody detects endogenous levels of total Bloom Syndrome protein. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Application Info | IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:1000 |
| Reference | V. Ashutosh Rao. AACR Meeting Abstracts, Mar 2004; 2004: 1244. Xiaobing Du. Mol. Cell. Biol., Oct 2004; 24: 8437 - 8446. Patricia L. Opresko. J. Biol. Chem., Oct 2002; 277: 41110 - 41119. |
| Gene Symbol | BLM |
|---|---|
| Gene Full Name | BLM RecQ like helicase |
| Alias Symbols | Bloom syndrome protein;Bloom syndrome RecQ like helicase;Bloom syndrome, RecQ helicase-like;BS;DNA helicase, RecQ-like type 2;MGRISCE1;recQ protein-like 3;RECQ2;RECQL2;RECQL3. |
| NCBI Gene Id | 641 |
| Protein Name | Bloom syndrome protein |
| Description of Target | ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction (PubMed:9388193, PubMed:24816114, PubMed:25901030). Participates in DNA replication and repair (PubMed:12019152, PubMed:21325134, PubMed:23509288). Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA (PubMed:21325134). Negatively regulates sister chromatid exchange (SCE) (PubMed:25901030). Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution (PubMed:25901030). Binds single-stranded DNA (ssDNA), forked duplex DNA and DNA Holliday junction (PubMed:20639533, PubMed:24257077, PubMed:25901030). |
| Uniprot ID | P54132 |
| Protein Accession # | NP_000048.1 |
| Molecular Weight | 159 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "BLM Antibody (OAAF00937)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "BLM Antibody (OAAF00937)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "BLM Antibody (OAAF00937)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "BLM Antibody (OAAF00937)"?
This target may also be called "Bloom syndrome protein;Bloom syndrome RecQ like helicase;Bloom syndrome, RecQ helicase-like;BS;DNA helicase, RecQ-like type 2;MGRISCE1;recQ protein-like 3;RECQ2;RECQL2;RECQL3." in publications.
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What is the shipping cost for "BLM Antibody (OAAF00937)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "BLM Antibody (OAAF00937)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "BLM Antibody (OAAF00937)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "159 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "BLM Antibody (OAAF00937)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "BLM"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "BLM"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "BLM"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "BLM"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "BLM"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "BLM"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
