Biotinylated CCL2 Protein (OPCB00020)

Catalog No: OPCB00020

Size:2ug

Product Info

• Product Format: Lyophilized
• Conjugation: Biotin
• Application: CA
• Additional Information: Extinction Coefficient: 14,180 M-1 cm-1
  Endotoxin Level: < 0.01 EU per 1ug of the protein by the LAL method
• Reconstitution and Storage: Centrifuge before opening. Suggest to use immediately after reconstitution. Reconstitute with 100 ug/ml in sterile water. Stable for at least 1 month at -20C to -70C under sterile conditions after reconstitution. 12 months from date of receipt, -20C to -70C as supplied.
• Purity: > 97% by HPLC
• Biological Activity: EC50 = 1.26 nM determined by Migration Assay of THP-1 cells
• Source: E. coli

Target Info

• Gene Symbol: CCL2
• Gene Full Name: chemokine (C-C motif) ligand 2
• Alias Symbols: HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30
• NCBI Gene Id: 6347
• Description of Target: Monocyte chemoattractant protein-1 (MCP-1) (CCL2) is produced by many cell types at sites of inflammation. It regulates chemotaxis and transendothielial migration of monocytes, as well as memory T cells and natural killer cells by interacting with their membrane surface receptor CCR2. MCP-1 has also been implicated in a number of disease states, such as rheumatoid arthritis, atherosclerosis, autoimmune diseases, tumor progression, and HIV infection.
• Uniprot ID: P13500
• Molecular Weight: 11 kDa