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Catalog No: OPPA02456 (Formerly GWB-BSP402)
Size:5UG
Price: $75.00
SKU
OPPA02456
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BIN1 Protein (OPPA02456)

Datasheets/ManualsPrintable datasheet for OPPA02456
Product Info
Predicted Species ReactivityHuman
Product FormatSterile filtered colorless solution.
HostE. Coli
::Product Introduction: BIN1 is a nucleocytoplasmic adaptor protein, one of which was primarily identified as MYC-interacting protein having the characteristics of a tumor suppressor. BIN1 protein interacts with and inhibits the oncogenic activity of the myc oncoprotein that is a key player in many human cancers. The absence of Bin1 contributes to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver.
Product Description: BIN1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 459 amino acids (1-439 a.a.) and having a molecular mass of 50.4 kDa. The BIN1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Reconstitution and StorageBIN1 Human although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles.
PurityGreater than 90.0% as determined by SDS-PAGE.
Peptide SequenceMGSSHHHHHH SSGLVPRGSH MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN FNKQLTEGTR LQKDLRTYLA SVKAMHEASK KLNECLQEVY EPDWPGRDEA NKIAENNDLL WMDYHQKLVD QALLTMDTYL GQFPDIKSRI AKRGRKLVDY DSARHHYESL QTAKKKDEAK IAKAEEELIK AQKVFEEMNV DLQEELPSLW NSRVGFYVNT FQSIAGLEEN FHKEMSKLNQ NLNDVLVGLE KQHGSNTFTV KAQPSDNAPA KGNKSPSPPD GSPAATPEIR VNHEPEPAGG ATPGATLPKS PSQPAEASEV AGGTQPAAGA QEPGETAASE AASSSLPAVV VETFPATVNG TVEGGSGAGR LDLPPGFMFK VQAQHDYTAT DTDELQLRAG DVVLVIPFQN PEEQDEGWLM GVKESDWNQH KELEKCRGVF PENFTERVP.
Gene SymbolBIN1
Alias SymbolsCNM2, AMPH2, AMPHL, SH3P9
NCBI Gene Id274
Protein NameMyc box-dependent-interacting protein 1
Description of TargetRecombinant Human Bridging Integrator 1
Uniprot IDO00499
Protein Accession #NP_004296.1
Protein Size (# AA)Recombinant
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