Bim Antibody (OAPB01346)

Catalog No: OAPB01346

Size:100UG

Click here to learn more about Aviva's By-Request Conjugation Service.

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid. Bim Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Monoclonal
• Host: Bim monoclonal antibody was raised in mouse.
  Please use anti-mouse secondary antibodies.
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: Bim monoclonal antibody can be stored at 4C, stable for one year.
• Immunogen: Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 1 mg/ml
• Application Info: Bim antibody can be used for detection of Bim by Western blot at 0.5 – 1 ug/mL. (Optimal dilution should be determined by user)
• Reference: O'Connor L, Strasser A, O'Reilly LA, et al. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 1998; 17:384-395.;Hsu SY, Lin P, and Hsueh AJ BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol. Endocrinol. 1998; 12:1432-40. ;

Target Info

• Gene Symbol: BCL2L11
• Gene Full Name: BCL2 like 11
• Alias Symbols: BAM;bcl-2 interacting mediator of cell death;bcl-2 interacting protein Bim;Bcl2-interacting mediator of cell death;BCL2-like 11 (apoptosis facilitator);bcl-2-like protein 11;bcl-2-related ovarian death agonist;BIM;BOD.
• NCBI Gene Id: 10018
• Protein Name: Bcl-2-like protein 11|bcl-2-like protein 11 isoform 1 [Homo sapiens]
• Description of Target: Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
• Uniprot ID: O43521
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_619527