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BICC1 Antibody - N-terminal region (OAAB04089)

400ul
$390.00
In Stock
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Gene Symbol:
BICC1
NCBI Gene Id:
80114
Protein Name:
Protein bicaudal C homolog 1
Swissprot Id:
Q9H694
Protein Accession #:
NP_001073981.1
Alias Symbols:
Protein bicaudal C homolog 1, Bic-C, BICC1
Replacement Item:
This antibody may replace item sc-162569 from Santa Cruz Biotechnology.
Description of Target:
BICC1 is an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.
Molecular Weight:
105 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Application:
WB, IHC-P, ELISA
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BICC1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BICC1.
Immunogen:
This BICC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-107 amino acids from the N-terminal region of human BICC1.
Predicted Species Reactivity:
Human, Xenopus, Mouse
Product Format:
Liquid. PBS with 0.09% (W/V) sodium azide.
Reconstitution and Storage:
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration:
0.47 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-BICC1 antibody - OAAB04089
Isotype:
Ig
Intended Use:
For research use only and not for use in diagnostic or therapeutic procedures.
Application Info:
WB: 1:1000
IHC-P: 1:10~50
Optimal dilutions should be determined by the end user.
Additional Information:
Function: Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development.
Cellular Location: Cytoplasm
Target Reference:
Grupe,A., et.al., Am. J. Hum. Genet. 78 (1), 78-88 (2006)
Publications:

Gamberi, C; Hipfner, DR; Trudel, M; Lubell, WD; Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila. 13, e1006694 (2017). WB, IHC, ELISA, Human 28406902

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