Size:400ul
$329.00
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SKU
OAAB04089
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BICC1 Antibody - N-terminal region (OAAB04089)

Catalog#: OAAB04089
Domestic: within 1 week delivery International: 1 week
This product is Genway GWB-ABBFUN
More Information
Predicted Species Reactivity Human, Xenopus, Mouse
Product Format Liquid. PBS with 0.09% (W/V) sodium azide.
Clonality Polyclonal
Isotype Ig
Host Rabbit
Application WB, IHC-P
Additional Information Function: Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development.
Cellular Location: Cytoplasm
Reconstitution and Storage Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-162569 from Santa Cruz Biotechnology.
Immunogen This BICC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-107 amino acids from the N-terminal region of human BICC1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration 0.47 mg/ml
Datasheets/Manuals Printable datasheet for anti-BICC1 antibody - OAAB04089
Intended Use For research use only and not for use in diagnostic or therapeutic procedures.
Application Info WB: 1:1000
IHC-P: 1:10~50
Optimal dilutions should be determined by the end user.
Target Reference Grupe,A., et.al., Am. J. Hum. Genet. 78 (1), 78-88 (2006)
Publications

Gamberi, C; Hipfner, DR; Trudel, M; Lubell, WD; Bicaudal C mutation causes myc and TOR pathway up-regulation and polycystic kidney disease-like phenotypes in Drosophila. 13, e1006694 (2017). WB, IHC, ELISA, Human 28406902

Gene Symbol BICC1
Alias Symbols Protein bicaudal C homolog 1, Bic-C, BICC1
NCBI Gene Id 80114
Protein Name Protein bicaudal C homolog 1
Description of Target BICC1 is an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.
Swissprot Id Q9H694
Protein Accession # NP_001073981.1
Molecular Weight 105 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express BICC1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express BICC1.
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