betaTub56D Antibody (OAAD00221)

Catalog No: OAAD00221

Size:100 ug

Product Info

• Predicted Species Reactivity: Human, Rat
• Clonality: Monoclonal
• Clone: TUB-2
• Isotype: IgG1
• Host: Mouse
• Application: WB, IHC, IP
• Reconstitution and Storage: At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
• Immunogen: Tubulin from rat brain.
• Purification: Purified by the goat anti-mouse IgG Affinity chromatography.
• Specificity: Human, rat.
  No cross reactivity with other proteins.
• Formulation: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative.
• Application Info: Western blot At 2ug/ml with the appropriate system to detect beta Tubulin in cells and tissues.
  Immunohistochemistry(P) At 0.5-1ug/ml to detect beta Tubulin in formalin fixed and paraffin embedded tissues.
  Other applications have not been tested.
  Optimal dilutions should be determined by end user.
• Storage Buffer: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
• Reference: 1. Floyd-Smith, G. A.; de Martinville, B.; Francke, U. : A beta-tubulin expressed gene M40 (TUBB) is located on human chromosome 6 and two related pseudogenes are located on chromosomes 8 (TUBBP1) and 13 (TUBBP2). (Abstract) Cytogenet. Cell Genet. 40: 629, 1985.
  2. Floyd-Smith, G. A.; de Martinville, B.; Francke, U. : An expressed beta-tubulin gene, TUBB, is located on the short arm of human chromosome 6 and two related sequences are dispersed on chromosomes 8 and 13. Exp. Cell Res. 163: 539-548, 1986.
  3 Monzo, M.; Rosell, R.; Sanchez, J. J.; Lee, J. S.; O'Brate, A.; Gonzalez-Larriba, J. L.; Alberola, V.; Lorenzo, J. C.; Nunez, L.; Ro, J. Y.; Martin, C. : aclitaxel resistance in non-small

Target Info

• Gene Symbol: betaTub56D
• Gene Full Name: Tubulin beta-1 chain
• Alias Symbols: 1t, A1ZBL0_DROME, B1t, beta, BETA 56D, beta-tub, beta-Tub, beta-tub 56D, beta-tub56D, beta-Tub56D, beta-tubulin, beta-tubulin56D, beta1, beta1-tub, beta1-Tubulin, beta1t, beta1tub, beta1Tub, beta56D, betaTub, betatub(56D), betaTub1, betatub56D, BetaTub56D
• NCBI Gene Id: 37238
• Protein Name: Tubulin beta-1 chain
• Description of Target: Tubulin beta (TUBB) was derived from its corresponding mRNA with a molecular weight of about 55, 000.
  TUBB gene contains 4 exons and located in the HLA class I region at 6p21.3. Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations
• Uniprot ID: Q24560
• Protein Accession #: NP_523795.2
• Nucleotide Accession #: NM_079071.3