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BD 1 Protein (OOPA00055)

Catalog#: OOPA00055
Domestic: within 1 week delivery | International: 1 week
This product is Genway GWB-BSP011
More Information
Product Format Sterile Filtered White lyophilized (freeze-dried) powder.
Host Escherichia Coli.
Additional Information Solubility: It is recommended to Reconstitution: Reconstitute the lyophilized Mouse BD-1 in sterile 18M?-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
:: Product Introduction: The Defensin family are highly similar in their protein sequence and are microbicidal & cytotoxic peptides made by neutrophils. Beta Defensin-1 is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. Beta Defensin-1 has close proximity to Defensin Alpha-1 and has been implicated in the pathogenesis of cystic fibrosis. Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human Beta Defensin-1 mRNA expression and higher human Beta Defensin-2 and human Beta Defensin-3 mRNA expression. Beta Defensin is highly expressed by epithelial cells. Beta-defensin 1 may play a role in the pathogenesis of severe sepsis.
Product Description: BD 1 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 37 amino acids and having a molecular mass of 4.1 KDa. The BD 1 Mouse is purified by proprietary chromatographic techniques.
Reconstitution and Storage Lyophilized Mouse BD 1 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution BD 1 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Formulation Lyophilized from a 0.2um filtered concentrated solution in PBS, pH7.4.
Purification Greater than 97.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
Purity Greater than 97.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
Biological Activity Measured by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/ml.
Datasheets/Manuals Printable datasheet for OOPA00055
Gene Symbol BD 1
Alias Symbols Beta-defensin 1, BD-1, Defensin beta 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822.
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