Catalog No: ARP30475_T100-FITC
Size:100ul
Price: $384.00
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ARP30475_T100-FITC
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BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)

Datasheets/ManualsPrintable datasheet for anti-BCL2L1 (ARP30475_T100-FITC) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationFITC: Fluorescein Isothiocyanate
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human BCL2L1
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%; Rat: 93%; Sheep: 100%
Peptide SequenceSynthetic peptide located within the following region: SNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAING
Concentration0.5 mg/ml
Blocking PeptideFor anti-BCL2L1 (ARP30475_T100-FITC) antibody is Catalog # AAP30475 (Previous Catalog # AAPP24055)
Sample Type Confirmation

BCL2L1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

ReferenceAllikmets,R., (2006) J. Mol. Biol. 356 (2), 367-381
Gene SymbolBCL2L1
Gene Full NameBCL2-like 1
Alias SymbolsBCLX, BCL2L, Bcl-X, PPP1R52, BCL-XL/S
NCBI Gene Id598
Protein NameBcl-2-like protein 1
Description of TargetBCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Uniprot IDQ07817
Protein Accession #NP_612815
Nucleotide Accession #NM_138578
Protein Size (# AA)233
Molecular Weight26kDa
Protein InteractionsBCL2L1; BCL2; BAX; BAD; BMF; BBC3; CASP8AP2; BECN1; UBC; TPT1; TP53BP2; ced-9; ced-4; PGAM5; CDKN2A; CASP1; BCL2L11; HRK; PMAIP1; BIK; BID; PARK2; PINK1; BAK1; RAD9A; AKT1; Mapk1; ATXN3; CLU; BCAP31; CRYAB; CRYAA; BFAR; PPP1CC; PPP1CA; ACTB; UBR1; METTL23
  1. What is the species homology for "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep".

  2. How long will it take to receive "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)"?

    This target may also be called "BCLX, BCL2L, Bcl-X, PPP1R52, BCL-XL/S" in publications.

  5. What is the shipping cost for "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "26kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BCL2L1 Antibody - N-terminal region : FITC (ARP30475_T100-FITC)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BCL2L1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BCL2L1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BCL2L1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BCL2L1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BCL2L1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BCL2L1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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