SAVE NOW with 10% off all Recombinant Antibodies Shop Now

Catalog No: OAAF01248 (Formerly GWB-ASC636)
Size:100 ug
Price: $344.00
SKU
OAAF01248
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for BCL2 Antibody (OAAF01248)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid PBS (without Mg2+ and Ca2+) pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationELISA, ICC, IF, IHC, IHC-P, WB
Reconstitution and Storage-20°C
ImmunogenThe antiserum was produced against synthesized peptide derived from human BCL-2.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
SpecificityBCL-2(Ab-56) Antibody detects endogenous levels of total BCL-2 protein.
DilutionThe optimal working dilution should be determined by the end user.
Application InfoWB: 1:500~1000
IHC: 1:50~100
ELISA: 1:10000
ReferenceLing, Y. H. et al. (1998) J. Biol. Chem. 273, 18984-18991.
Huang, S.J. and Cidlowski, J.A. (2002) FASEB 16, 825-832.
Deng, X. et al. (2001) J. Biol. Chem. 276, 23681-23688.
Huang ST,et al. (2002) FASEB J Jun; 16(8): 825-32.
Yamamoto, K. et al. (1999) Mol. Cell. Biol. 19, 8469-8478.
Gene SymbolBCL2
Gene Full NameBCL2 apoptosis regulator
Alias Symbolsapoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1, regulatory subunit 50.
NCBI Gene Id596
Protein NameApoptosis regulator Bcl-2
Description of TargetSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Uniprot IDP10415
Protein Accession #NP_000624.2
Molecular Weight26 kDa
  1. What is the species homology for "BCL2 Antibody (OAAF01248)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "BCL2 Antibody (OAAF01248)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "BCL2 Antibody (OAAF01248)" provided in?

    This item is provided in "Liquid PBS (without Mg2+ and Ca2+) pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BCL2 Antibody (OAAF01248)"?

    This target may also be called "apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1, regulatory subunit 50." in publications.

  5. What is the shipping cost for "BCL2 Antibody (OAAF01248)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BCL2 Antibody (OAAF01248)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BCL2 Antibody (OAAF01248)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "26 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BCL2 Antibody (OAAF01248)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BCL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BCL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BCL2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BCL2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BCL2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BCL2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:BCL2 Antibody (OAAF01248)
Your Rating
We found other products you might like!