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Catalog No: OAGA01004
Size:100 ul
Price: $372.00
SKU
OAGA01004
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-BCCIP antibody - OAGA01004
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationICC, IF, IHC-FFPE, WB
Additional InformationBackground: This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
::Positive Controls: A431, HeLa
::Cellular Localization: Nucleus
Reconstitution and StorageKeep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
ImmunogenSynthetic peptide corresponding to a region within amino acids 181 and 273 of BCCIP (Uniprot ID#Q9P287)
PurificationPurified by antigen-affinity chromatography.
Concentration1 mg/ml
Application InfoSuggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene SymbolBCCIP
Gene Full NameBRCA2 and CDKN1A-interacting protein
Alias SymbolsTOK1, TOK-1
NCBI Gene Id56647
Protein NameBRCA2 and CDKN1A-interacting protein
Uniprot IDQ9P287
Protein Accession #NP_057651.1
Molecular Weight36 kDa
  1. What is the species homology for "BCCIP Antibody (OAGA01004)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "BCCIP Antibody (OAGA01004)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "BCCIP Antibody (OAGA01004)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BCCIP Antibody (OAGA01004)"?

    This target may also be called "TOK1, TOK-1" in publications.

  5. What is the shipping cost for "BCCIP Antibody (OAGA01004)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BCCIP Antibody (OAGA01004)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BCCIP Antibody (OAGA01004)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "36 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BCCIP Antibody (OAGA01004)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BCCIP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BCCIP"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BCCIP"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BCCIP"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BCCIP"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BCCIP"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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