BCAR1 Antibody - middle region (OAEB03174)

Catalog No: OAEB03174

Size:100ug

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Dog
• Product Format: Liquid. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Clonality: Polyclonal
• Host: Goat
• Application: WB, IHC
• Reconstitution and Storage: Aliquot and store at -20C. Minimize freezing and thawing.
• Immunogen: Peptide with sequence C-KQTSTFSKQTPHH, from the internal region of the protein sequence according to NP_001164185.1; NP_001164186.1; NP_001164187.1; NP_001164188.1; NP_001164189.1; NP_055382.2; NP_001164190.1; NP_001164191.1; NP_001164192.1.
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Peptide Sequence: Synthetic peptide located within the following region: KQTSTFSKQTPHH
• Specificity: This antibody is expected to recognize reported isoforms 1, 2, 3, 5, 6 and 7.
• Epitope: middle region
• Application Info: Western Blot: Approx 100kDa band observed in lysates of Human breast cancer and of cell line MCF7 (calculated MW of 97.9kDa according to NP_001164185.1). Recommended concentration: 1-3ug/ml.
  Peptide ELISA: antibody detection limit dilution 1:128000.
  IHC: In paraffin embedded Human Uterus shows strong staining at the glandular side of the endometrial epithelium. Recommended concentration, 5-10ug/ml.
• Publications:

  Platelet-derived growth factor receptor-a and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 313, L1174-L1187 (2017). 28775097

Target Info

• Gene Symbol: BCAR1
• Alias Symbols: CAS, CAS1, CASS1, CRKAS, P130Cas
• NCBI Gene Id: 9564(Human); 12927 (mouse); 25414 (rat);
• Protein Accession #: NP_001164185.1;
  NP_001164186.1;
  NP_001164187.1;
  NP_001164188.1;
  NP_001164189.1;
  NP_055382.2;
  NP_001164190.1;
  NP_001164191.1;
  NP_001164192.1;
• Molecular Weight: 97.9 kDa