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Catalog No: ARP59803_P050
Price: $0.00
SKU
ARP59803_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-BBS10 (ARP59803_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human BBS10
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHuman: 100%; Rabbit: 86%
Peptide SequenceSynthetic peptide located within the following region: SQTGLESVMGKYQLLTSVLQCLTKILTIDMVITVKRHPQKVHNQDSEDEL
Concentration0.5 mg/ml
Blocking PeptideFor anti-BBS10 (ARP59803_P050) antibody is Catalog # AAP59803 (Previous Catalog # AAPP45962)
Sample Type Confirmation

BBS10 is supported by BioGPS gene expression data to be expressed in HEK293T

Gene SymbolBBS10
Gene Full NameBardet-Biedl syndrome 10
Alias SymbolsC12orf58
NCBI Gene Id79738
Protein NameBardet-Biedl syndrome 10 protein
Description of TargetThis gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.
Uniprot IDQ8TAM1
Protein Accession #NP_078961
Nucleotide Accession #NM_024685
Protein Size (# AA)723
Molecular Weight81kDa
Protein InteractionsUBC; YAE1D1; MAPK8IP2; HDAC6; TNFSF11; MAP3K7; RGS2; RASA1; PTK2; MAPK6; NR4A1; FRZB; CSNK1E;
  1. What is the species homology for "BBS10 Antibody - C-terminal region (ARP59803_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rabbit".

  2. How long will it take to receive "BBS10 Antibody - C-terminal region (ARP59803_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "BBS10 Antibody - C-terminal region (ARP59803_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BBS10 Antibody - C-terminal region (ARP59803_P050)"?

    This target may also be called "C12orf58" in publications.

  5. What is the shipping cost for "BBS10 Antibody - C-terminal region (ARP59803_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BBS10 Antibody - C-terminal region (ARP59803_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BBS10 Antibody - C-terminal region (ARP59803_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "81kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BBS10 Antibody - C-terminal region (ARP59803_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BBS10"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BBS10"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BBS10"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BBS10"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BBS10"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BBS10"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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