BBC3 Antibody - middle region (ARP96868_P050)

Catalog No: ARP96868_P050

Host: Rabbit
Target Name: BBC3
Sample Tissue: Human Jurkat Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BBC3
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: TVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPAL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-BBC3 (ARP96868_P050) antibody is Catalog # AAP96868

Target Info

• Gene Symbol: BBC3
• Gene Full Name: BCL2 binding component 3
• Alias Symbols: JFY1, PUMA, JFY-1
• NCBI Gene Id: 27113
• Protein Name: Bcl-2-binding component 3
• Description of Target: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
• Uniprot ID: Q96PG8
• Protein Accession #: NP_001120712.1
• Nucleotide Accession #: NM_001127240.2
• Protein Size (# AA): 261
• Molecular Weight: 28 kDa