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Datasheets/Manuals | Printable datasheet for BAZ2A Antibody (OAAF03395) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human BAZ2A. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity | BAZ2A antibody detects endogenous levels of total BAZ2A protein. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | WB 1:500~1000 ELISA 1:10000 |
Reference | Jones M.H., Genomics 63:40-45(2000). Bechtel S., BMC Genomics 8:399-399(2007). Scherer S.E., Nature 440:346-351(2006). |
Gene Symbol | BAZ2A |
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Gene Full Name | bromodomain adjacent to zinc finger domain 2A |
Alias Symbols | bromodomain adjacent to zinc finger domain protein 2A;hWALp3;TIP5;transcription termination factor I-interacting protein 5;TTF-I interacting peptide 5;TTF-I-interacting protein 5;WALp3. |
NCBI Gene Id | 11176 |
Protein Name | Bromodomain adjacent to zinc finger domain protein 2A |
Description of Target | Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity). |
Uniprot ID | Q9UIF9 |
Protein Accession # | NP_038477.2 |
Molecular Weight | 208 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "BAZ2A Antibody (OAAF03395)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "BAZ2A Antibody (OAAF03395)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "BAZ2A Antibody (OAAF03395)" provided in?
This item is provided in "Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "BAZ2A Antibody (OAAF03395)"?
This target may also be called "bromodomain adjacent to zinc finger domain protein 2A;hWALp3;TIP5;transcription termination factor I-interacting protein 5;TTF-I interacting peptide 5;TTF-I-interacting protein 5;WALp3." in publications.
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What is the shipping cost for "BAZ2A Antibody (OAAF03395)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "BAZ2A Antibody (OAAF03395)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "BAZ2A Antibody (OAAF03395)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "208 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "BAZ2A Antibody (OAAF03395)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "BAZ2A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "BAZ2A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "BAZ2A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "BAZ2A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "BAZ2A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "BAZ2A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.