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BAX Antibody - N-terminal region (OASG00713)

100 uL
$215.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC, ELISA
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Gene Symbol:
BAX
Official Gene Full Name:
BCL2-associated X protein
NCBI Gene Id:
581;
Swissprot Id:
Q07815
Replacement Item:
This antibody may replace item sc-20067 from Santa Cruz Biotechnology.
Description of Target:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Molecular Weight:
24 kDa
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BAX.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BAX.
Immunogen:
Synthesized peptide derived from the N-terminal region of human Bax. Location: 10-90aa.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-BAX (OASG00713) antibody
Specificity:
Bax Polyclonal Antibody detects endogenous levels of Bax protein.
Application Info:
IHC 1:100-1:300; ELISA 1:20000;

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