BAP3 Antibody (OAPB00643)

Catalog No: OAPB00643

Size:100UG

Western blot analysis of BAP3 in SK-N-SH cell lysate with BAP3 antibody at 2 ug/mL.

Immunohistochemical staining of human brain tissue using BAP3 antibody at 2.5 ug/mL.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. BAP3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: BAP3 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: BAP3 antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human BAP3. The immunogen is located within the first 50 amino acids of BAP3.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-BAP3 antibody is Catalog # OEPB02767
• Application Info: BAP3 antibody can be used for the detection of BAP3 by Western blot at 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Shiratsuchi T, Oda K, Nishimori H, et al. Cloning and characterization of BAP (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. Biochem. Biophys. Res. Comm.1998; 251:158-65. ;Palmer RE, Lee SB, Wong JC, et al. Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis. Cancer Cell2002; 2:497-505.;

Target Info

• Gene Symbol: BAIAP3
• Gene Full Name: BAI1 associated protein 3
• Alias Symbols: BAI1-associated protein 3;BAI-associated protein 3;BAP3;brain-specific angiogenesis inhibitor I-associated protein 3.
• NCBI Gene Id: 8938
• Protein Name: BAI1-associated protein 3|BAI-associated protein 3 [Homo sapiens]
• Description of Target: Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin (PubMed:28626000). Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission (By similarity).
• Uniprot ID: O94812
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/BAA34710