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BAG2 Antibody (OAGA05647)

100 ul
$409.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ICC, IF, IHC-P, WB
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Gene Symbol:
BAG2
Official Gene Full Name:
BCL2 associated athanogene 2
NCBI Gene Id:
9532
Protein Name:
BAG family molecular chaperone regulator 2
Swissprot Id:
O95816
Protein Accession #:
NP_004273.1
Nucleotide Accession #:
NM_004282.3
Alias Symbols:
BAG-2, dJ417I1.2
Description of Target:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BAG2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BAG2.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human BAG2. The exact sequence is proprietary.
Concentration:
0.84 mg/ml
Datasheets/Manuals:
Printable datasheet for OAGA05647
Preservative:
0.01% Thimerosal
Application Info:
Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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