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BAG2 Antibody (OAAN02418)

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Gene Symbol:
BAG2
Official Gene Full Name:
BCL2 associated athanogene 2
NCBI Gene Id:
9532
Protein Name:
BAG family molecular chaperone regulator 2
Swissprot Id:
O95816
Protein Accession #:
NP_004273.1
Nucleotide Accession #:
NM_004282.3
Alias Symbols:
BAG-2, dJ417I1.2, BAG-2, dJ417I1.2, BCL2 associated athanogene 2, BAG family molecular chaperone regulator 2, BAG2
Description of Target:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Molecular Weight:
24 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified against immunogen
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express BAG2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express BAG2.
Immunogen:
Recombinant protein of human BAG2
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-BAG2 (OAAN02418)
Preservative:
0.02% Sodium Azide
Conjugation:
Unconjugated
Isotype:
IgG
Application Info:
WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200
Storage Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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