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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for OAAQ00148 |
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Tested Species Reactivity | Human, Mouse, Rat |
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Predicted Species Reactivity | Mouse, Rat |
Product Format | Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA. |
Clonality | Monoclonal |
Clone | BADS112-B9 |
Isotype | Rabbit IgG1L |
Host | Rabbit |
Conjugation | Unconjugated |
Application | FC |
Reconstitution and Storage | -20C |
Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD |
Purification | Protein A+G |
Target Post-Translational Modification | Phospho-Ser112 |
Application Info | 1ug/mL - 0.001ug/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information. |
Reference | Czabotar PE., et al., (2014) Nat Rev Mol Cell Biol 15:49-63. Polzien L., et al., (2009) J Biol Chem 284:28004-28020. Masters SC., et al., (2001) Mol Pharmacol 60: 1325-1331. Datta SR., et al., (1997) Cell 91:231-241. Harada H., et al., (1999) Mol Cell 3:413-422. Chiang CW et al., (2001) Blood 97:1289-1297. |
Gene Symbol | BAD |
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Gene Full Name | BCL2 associated agonist of cell death |
Alias Symbols | BBC2, BCL2L8 |
NCBI Gene Id | 572 |
Protein Name | bcl2-associated agonist of cell death |
Description of Target | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
Uniprot ID | Q92934 |
Protein Accession # | NP_004313.1 |
Nucleotide Accession # | NM_004322.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)"?
The tested species reactivity for this item is "Human, Mouse, Rat". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)" provided in?
This item is provided in "Liquid. 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)"?
This target may also be called "BBC2, BCL2L8" in publications.
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What is the shipping cost for "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Human BAD Antibody (Phospho-Ser112) (OAAQ00148)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "BAD"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "BAD"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "BAD"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "BAD"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "BAD"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "BAD"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.