BACE2 Recombinant Protein (OPCD01574)

Catalog No: OPCD01574

BACE2 Recombinant Protein (OPCD01574) using SDS-PAGE

BACE2 Recombinant Protein (OPCD01574) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Glu156-Val407
  Subcellular Location: Membrane; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome. Cell surfac
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: Bace2
• Gene Full Name: beta-site APP-cleaving enzyme 2
• Alias Symbols: 1110059C24Rik;A;AEPLC;AI850424;AL;ALP56;ARP1;AS;ASP1;ASP21;aspartyl protease 1;BAE;BAE2;beta-secretase 2;beta-site amyloid precursor protein cleaving enzyme 2;CDA1;CDA13;CEA;CEAP1;DRAP;memapsin-1;membrane-associated aspartic protease 1;theta-secretase.
• NCBI Gene Id: 56175
• Protein Name: Beta-secretase 2
• Description of Target: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity).
• Uniprot ID: Q9JL18
• Protein Accession #: NP_062390.3
• Nucleotide Accession #: NM_019517.5
• Protein Size (# AA): Glu156~Val407
• Molecular Weight: 58kDa