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Catalog No: ARP46852_P050-Biotin
Size:100ul
Price: $434.00
SKU
ARP46852_P050-Biotin
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)

Datasheets/ManualsPrintable datasheet for anti-BACE2 (ARP46852_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human BACE2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%; Zebrafish: 92%
Peptide SequenceSynthetic peptide located within the following region: SLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGF
Concentration0.5 mg/ml
Blocking PeptideFor anti-BACE2 (ARP46852_P050-Biotin) antibody is Catalog # AAP46852 (Previous Catalog # AAPP27648)
Sample Type Confirmation

BACE2 is supported by BioGPS gene expression data to be expressed in ACHN

Gene SymbolBACE2
Gene Full NameBeta-site APP-cleaving enzyme 2
Alias SymbolsASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1
NCBI Gene Id25825
Protein NameBeta-secretase 2
Description of TargetCerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
Uniprot IDQ9Y5Z0
Protein Accession #NP_620477
Nucleotide Accession #NM_138992
Protein Size (# AA)396
Molecular Weight37kDa
Protein InteractionsUBC; BACE2; APP; GGA1; GGA2;
  1. What is the species homology for "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)"?

    This target may also be called "ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1" in publications.

  5. What is the shipping cost for "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "37kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "BACE2 Antibody - middle region : Biotin (ARP46852_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "BACE2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "BACE2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "BACE2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "BACE2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "BACE2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "BACE2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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