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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for BACE1 Antibody (OAAF00666) |
|---|
| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin |
| Reconstitution and Storage | -20°C |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BACE. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Specificity | BACE antibody detects endogenous levels of total BACE protein. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Application Info | IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:1000 |
| Reference | Vassar R., Science 286:735-741(1999). Sinha S., Nature 402:537-540(1999). Yan R., Nature 402:533-537(1999) |
| Gene Symbol | BACE1 |
|---|---|
| Gene Full Name | beta-secretase 1 |
| Alias Symbols | APP beta-secretase;asp 2;ASP2;aspartyl protease 2;BACE;beta-secretase 1;beta-secretase 1 precursor variant 1;beta-site amyloid beta A4 precursor protein-cleaving enzyme;Beta-site amyloid precursor protein cleaving enzyme 1;beta-site APP cleaving enzyme 1;beta-site APP-cleaving enzyme;HSPC104;memapsin-2;membrane-associated aspartic protease 2;transmembrane aspartic proteinase Asp2. |
| NCBI Gene Id | 23621 |
| Protein Name | Beta-secretase 1 |
| Description of Target | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. |
| Uniprot ID | P56817 |
| Protein Accession # | NP_001193978.1 |
| Molecular Weight | 55 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "BACE1 Antibody (OAAF00666)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "BACE1 Antibody (OAAF00666)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "BACE1 Antibody (OAAF00666)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "BACE1 Antibody (OAAF00666)"?
This target may also be called "APP beta-secretase;asp 2;ASP2;aspartyl protease 2;BACE;beta-secretase 1;beta-secretase 1 precursor variant 1;beta-site amyloid beta A4 precursor protein-cleaving enzyme;Beta-site amyloid precursor protein cleaving enzyme 1;beta-site APP cleaving enzyme 1;beta-site APP-cleaving enzyme;HSPC104;memapsin-2;membrane-associated aspartic protease 2;transmembrane aspartic proteinase Asp2." in publications.
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What is the shipping cost for "BACE1 Antibody (OAAF00666)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "BACE1 Antibody (OAAF00666)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "BACE1 Antibody (OAAF00666)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "55 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "BACE1 Antibody (OAAF00666)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "BACE1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "BACE1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "BACE1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "BACE1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "BACE1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "BACE1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
