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B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)
Datasheets/Manuals | Printable datasheet for anti-B4GALT1 (ARP76190_P050-FITC) antibody |
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Predicted Species Reactivity | Human |
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Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | FITC: Fluorescein Isothiocyanate |
Application | WB |
Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Immunogen | The immunogen is a synthetic peptide directed towards the C-terminal region of Human B4GT1 |
Purification | Affinity purified |
Peptide Sequence | Synthetic peptide located within the following region: MIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQVLDVQRYPLYTQ |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-B4GALT1 (ARP76190_P050-FITC) antibody is Catalog # AAP76190 |
Reference | N/A |
Gene Symbol | B4GALT1 |
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Gene Full Name | beta-1,4-galactosyltransferase 1 |
Alias Symbols | GT1, GTB, CDG2D, GGTB2, B4GAL-T1, beta4Gal-T1 |
NCBI Gene Id | 2683 |
Protein Name | beta-1,4-galactosyltransferase 1 |
Description of Target | This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase. |
Uniprot ID | P15291 |
Protein Accession # | NP_001488 |
Protein Size (# AA) | 398 |
Molecular Weight | 43kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)"?
This target may also be called "GT1, GTB, CDG2D, GGTB2, B4GAL-T1, beta4Gal-T1" in publications.
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What is the shipping cost for "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "43kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "B4GALT1 Antibody - C-terminal region : FITC (ARP76190_P050-FITC)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "B4GALT1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "B4GALT1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "B4GALT1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "B4GALT1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "B4GALT1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "B4GALT1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.