Catalog No: OPCD01566
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OPCD01566
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Datasheets/ManualsPrintable datasheet for B2M Recombinant Protein (OPCD01566)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Isoelectric Point: 6.5
::Residues: Gln22-Met119
::Subcellular Location: Secreted.
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolB2M
Gene Full Namebeta-2-microglobulin
Alias Symbolsbeta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;IMD43.
NCBI Gene Id567
Protein NameBeta-2-microglobulin
Description of TargetComponent of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Uniprot IDP61769
Protein Accession #NP_004039.1
Nucleotide Accession #NM_004048.2
Protein Size (# AA)Gln22~Met119
Molecular Weight13kDa
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