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Catalog No: OAAF03167 (Formerly GWB-ASE276)
Size:100 ug
Price: $344.00
SKU
OAAF03167
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for AZI1 Antibody (OAAF03167)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Reconstitution and Storage-20°C
ImmunogenThe antiserum was produced against synthesized peptide derived from human AZI1.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SpecificityAZI1 antibody detects endogenous levels of total AZI1 protein.
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
DilutionThe optimal working dilution should be determined by the end user.
Application InfoWB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:40000
ReferenceKikuno R., DNA Res. 6:197-205(1999).
Andersen J.S., Nature 426:570-574(2003).
Olsen J.V., Cell 127:635-648(2006).
Gene SymbolCEP131
Gene Full Namecentrosomal protein 131
Alias Symbols5-azacytidine induced 1;5-azacytidine-induced protein 1;AZ1;AZI1;centrosomal protein 131 kDa;centrosomal protein 131kDa;centrosomal protein of 131 kDa;pre-acrosome localization protein 1;ZA1.
NCBI Gene Id22994
Protein NameCentrosomal protein of 131 kDa
Description of TargetComponent of centriolar satellites contributing to the building of a complex and dynamic network required to regulate cilia/flagellum formation (PubMed:17954613, PubMed:24185901). In proliferating cells, MIB1-mediated ubiquitination induces its sequestration within centriolar satellites, precluding untimely cilia formation initiation (PubMed:24121310). In contrast, during normal and ultraviolet or heat shock cellular stress-induced ciliogenesis, its non-ubiquitinated form is rapidly displaced from centriolar satellites and recruited to centrosome/basal bodies in a microtubule- and p38 MAPK-dependent manner (PubMed:24121310, PubMed:26616734). Acts also as a negative regulator of BBSome ciliary trafficking (PubMed:24550735). Plays a role in sperm flagellar formation; may be involved in the regulation of intraflagellar transport (IFT) and/or intramanchette (IMT) trafficking, which are important for axoneme extension and/or cargo delivery to the nascent sperm tail (By similarity). Required for optimal cell proliferation and cell cycle progression; may play a role in the regulation of genome stability in non-ciliogenic cells (PubMed:22797915, PubMed:26297806). Involved in centriole duplication (By similarity). Required for CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806).
Uniprot IDQ9UPN4
Protein Accession #NP_001009811.2
Molecular Weight122 kDa
  1. What is the species homology for "AZI1 Antibody (OAAF03167)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "AZI1 Antibody (OAAF03167)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "AZI1 Antibody (OAAF03167)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AZI1 Antibody (OAAF03167)"?

    This target may also be called "5-azacytidine induced 1;5-azacytidine-induced protein 1;AZ1;AZI1;centrosomal protein 131 kDa;centrosomal protein 131kDa;centrosomal protein of 131 kDa;pre-acrosome localization protein 1;ZA1." in publications.

  5. What is the shipping cost for "AZI1 Antibody (OAAF03167)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AZI1 Antibody (OAAF03167)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AZI1 Antibody (OAAF03167)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "122 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AZI1 Antibody (OAAF03167)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CEP131"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CEP131"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CEP131"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CEP131"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CEP131"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CEP131"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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