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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for AUH Antibody (OACA07264) (OACA07264) |
|---|
| Predicted Species Reactivity | Human|Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Methylglutaconyl-CoA hydratase, mitochondrial protein (68-339AA) |
| Purification | Affinity Purified |
| Preservative | 0.02% sodium azide |
| Formulation | PBS with, 50% glycerol, pH7.3. |
| Reference | [1]"Mutations in the AUH gene cause 3-methylglutaconic aciduria type I." Ly T.B.N., Peters V., Gibson K.M., Liesert M., Buckel W., Wilcken B., Carpenter K., Ensenauer R., Hoffmann G.F., Mack M., Zschocke J.Hum. Mutat. 21:401-407(2003). [2]"Crystal structure of human AUH protein, a single-stranded RNA binding homolog of enoyl-CoA hydratase."Kurimoto K., Fukai S., Nureki O., Muto Y., Yokoyama S.Structure 9:1253-1263(2001). [3]"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014). |
| Gene Symbol | AUH |
|---|---|
| Gene Full Name | AU RNA binding methylglutaconyl-CoA hydratase |
| Alias Symbols | 3-methylglutaconyl-CoA hydratase;AU RNA binding protein/enoyl-CoA hydratase;AU RNA-binding protein/enoyl-Coenzyme A hydratase;AU-binding protein/Enoyl-CoA hydratase;AU-specific RNA-binding enoyl-CoA hydratase;itaconyl-CoA hydratase;methylglutaconyl-CoA hydratase, mitochondrial. |
| NCBI Gene Id | 549 |
| Protein Name | Methylglutaconyl-CoA hydratase, mitochondrial |
| Description of Target | Catalyzes the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA (PubMed:11738050, PubMed:12434311, PubMed:12655555). Also has itaconyl-CoA hydratase activity by converting itaconyl-CoA into citramalyl-CoA in the C5-dicarboxylate catabolism pathway (PubMed:29056341). The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite (PubMed:29056341). Has very low enoyl-CoA hydratase activity (PubMed:7892223). Was originally identified as RNA-binding protein that binds in vitro to clustered 5'-AUUUA-3' motifs (PubMed:7892223). |
| Uniprot ID | Q13825 |
| Protein Accession # | NP_001293119 |
| Nucleotide Accession # | NM_001306190 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "AUH Antibody (OACA07264)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Rat".
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How long will it take to receive "AUH Antibody (OACA07264)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "AUH Antibody (OACA07264)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "AUH Antibody (OACA07264)"?
This target may also be called "3-methylglutaconyl-CoA hydratase;AU RNA binding protein/enoyl-CoA hydratase;AU RNA-binding protein/enoyl-Coenzyme A hydratase;AU-binding protein/Enoyl-CoA hydratase;AU-specific RNA-binding enoyl-CoA hydratase;itaconyl-CoA hydratase;methylglutaconyl-CoA hydratase, mitochondrial." in publications.
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What is the shipping cost for "AUH Antibody (OACA07264)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "AUH Antibody (OACA07264)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "AUH Antibody (OACA07264)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "AUH Antibody (OACA07264)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "AUH"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "AUH"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "AUH"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "AUH"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "AUH"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "AUH"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
