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Catalog No: OARA02435 (Formerly GWB-B4E56F)
Size:100UG
Price: $594.00
SKU
OARA02435
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AUB Antibody (OARA02435)

Datasheets/ManualsPrintable datasheet for AUB Antibody (OARA02435)
Product Info
Predicted Species ReactivityDrosophila melanogaster
Product FormatLiquid (sterile filtered)
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Western blot
Reconstitution and StorageStore vial at -20C prior to opening. For extended storage, aliquot contents and freeze at -20C or below. Avoid cycles of freezing and thawing.This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Drosophila melanogaster Aubergine/Sting protein.
PurificationThe product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest limited cross reactivity with Aubergine protein from other sources.
Predicted Homology Based on Immunogen SequenceDrosophila melanogaster
Concentration1 mg/ml
SpecificityAnti-Aubergine affinity-purified antibody is directed against Drosophila Aubergine protein.
Application InfoELISA 1:6000~30000
IP 1:100
WB 1:500~3000
Application DataAubergine affinity-purified antibody has been tested for use in ELISA. Specific conditions for reactivity should be optimized by the end user. By western blot a band approximately 98 kDa in size corresponding to Aubergine protein is expected in the appropriate cell lysate or extract.
Gene Symbolaub
Gene Full Nameaubergine
Alias SymbolsAub;aubergine;aub-PA;aub-PC;CG6137;CG6137-PA;CG6137-PC;Dmel\CG6137;Dmel_CG6137;ms(2)32D;Protein sting;stellate-interacting gene;sti;sting.
NCBI Gene Id34524
Protein NameProtein aubergine
Description of TargetActs via the piwi-interacting RNA (piRNA) metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. In ovary, associates predominantly with antisense piRNAs that contain uridine at their 5' end. In testis, associates with Su(Ste) antisense piRNAs (most abundant class of piRNAs found in complex with aub in testes) and negatively regulates Ste expression, most likely by cleaving its transcripts. Also in testis, may repress translation of vas when associated with a piRNA derived from chromosome X, termed AT-chX-1, whose sequence shows strong complementarity to vas mRNA. Aub-piRNA complexes from ovary and testis possess RNA cleavage activity. Involved in telomere regulation by repressing specialized telomeric retroelements HeT-A and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements. Also involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans, in the female germline, a homologous transposon, or transgene located in euchromatin. Involved in the suppression of meiotic drive of sex chromosomes and autosomes. Involved in transposon silencing in the adult brain. Required for dorsal-ventral as well as anterior-posterior patterning of the egg. Required during oogenesis for primordial germ cell formation and activation of RNA interference. During early oogenesis, required for osk mRNA silencing and polarization of the microtubule cytoskeleton. During mid-oogenesis, required for osk mRNA localization to the posterior pole and efficient translation of osk and grk. During embryogenesis, required for posterior localization of nos mRNA, independently of osk, and pole cell formation. Essential for the formation and/or structural integrity of perinuclear nuage particles. Required for the localization of Mael to the meiotic nuage. Forms a complex with smg, twin, AGO3 and specific piRNAs that targets nos mRNA (and probably other maternal mRNAS) for deadenylation promoting its decay during early embryogenesis.
Uniprot IDO76922
  1. What is the species homology for "AUB Antibody (OARA02435)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Drosophila melanogaster".

  2. How long will it take to receive "AUB Antibody (OARA02435)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "AUB Antibody (OARA02435)" provided in?

    This item is provided in "Liquid (sterile filtered)".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AUB Antibody (OARA02435)"?

    This target may also be called "Aub;aubergine;aub-PA;aub-PC;CG6137;CG6137-PA;CG6137-PC;Dmel\CG6137;Dmel_CG6137;ms(2)32D;Protein sting;stellate-interacting gene;sti;sting." in publications.

  5. What is the shipping cost for "AUB Antibody (OARA02435)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AUB Antibody (OARA02435)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AUB Antibody (OARA02435)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AUB Antibody (OARA02435)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "aub"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "aub"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "aub"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "aub"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "aub"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "aub"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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