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ATXN3 Protein Lysate (APL10548)

200ug
$219.00
In Stock
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Gene Symbol:
ATXN3
Alias Symbols:
AT3, JOS, MJD, ATX3, MJD1, SCA3
NCBI Gene Id:
4287
Protein Name:
Ataxin-3
Swissprot Id:
P54252
Protein Accession #:
NP_004984
Nucleotide Accession #:
NM_001127696
Description of Target:
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ATXN3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ATXN3.
Protein Interactions:
UBC; NEDD8; ATXN3; TRIM63; SQSTM1; VCP; ITCH; PARK2; MGRN1; TUBB; HDAC6; TUBA1A; ELC1; ELA1; SYVN1; BAG3; BCL2L1; STUB1; SUMO1; APP; RFFL; TRIM55; SPRTN; PJA1; TRIM54; USP21; UBE2L3; ARHGDIA; ASIC1; RAD23B; RAD23A; ARHGAP19; C16orf70; TEX11; PICK1; GSK3B;
Quality Control:
This product was tested on western blot.
Tag:
GST
Reconstitution and Storage:
Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Datasheets/Manuals:
Printable datasheet for anti-ATXN3 (APL10548) antibody
Additional Information:
Buffer Formulation: 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.

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