ATXN1 Recombinant Protein (OPCD01549)

Catalog No: OPCD01549

ATXN1 Recombinant Protein (OPCD01549) using SDS-PAGE

ATXN1 Recombinant Protein (OPCD01549) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Pro331-Asp587
  Subcellular Location: Cytoplasm . Nucleus.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Atxn1
• Gene Full Name: ataxin 1
• Alias Symbols: 2900016G23Rik;ataxin-1;Atx;Atx1;C85907;Gm10786;Sc;Sca1;spinocerebellar ataxia 1 homolog;Spinocerebellar ataxia type 1 protein homolog.
• NCBI Gene Id: 20238
• Protein Name: Ataxin-1
• Description of Target: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity). May be involved in RNA metabolism (By similarity). In concert with CIC and ATXN1L, involved in brain development (PubMed:28288114).
• Uniprot ID: P54254
• Protein Accession #: NP_001186233.1
• Nucleotide Accession #: NM_001199304.1
• Protein Size (# AA): Pro331~Asp587
• Molecular Weight: 35kDa