ATP6V1B1 Antibody (OACA06853)

Catalog No: OACA06853

Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100

Immunohistochemistry of paraffin-embedded human salivary gland at dilution 1:100

All lanes: V-type proton ATPase subunit B, kidney isoform antibody at 7ug/ml
Lane 1: mouse kidney tissue
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/1,0000 dilution
Predicted band size: 57kDa
Observed band size: 57kDa

All lanes: V-type proton ATPase subunit B, kidney isoform antibody at 7ug/ml
Lane 1: mouse kidney tissue
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/1,0000 dilution
Predicted band size: 57kDa
Observed band size: 57kDa

Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100

Immunohistochemistry of paraffin-embedded human salivary gland at dilution 1:100

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human V-type proton ATPase subunit B, kidney isoform protein (1-280AA)
• Purification: Affinity Purified
• Preservative: 0.02% sodium azide
• Formulation: PBS with, 50% glycerol, pH7.3.
• Reference: [1]"Confirmation of the ATP6B1 gene as responsible for distal renal tubular acidosis."Ruf R., Rensing C., Topaloglu R., Guay-Woodford L., Klein C., Vollmer M., Otto E., Beekmann F., Haller M., Wiedensohler A., Leumann E., Antignac C., Rizzoni G., Filler G., Brandis M., Weber J.L., Hildebrandt F. Pediatr. Nephrol. 18:105-109(2003). [2]"Novel ATP6V1B1 and ATP6V0A4 mutations in autosomal recessive distal renal tubular acidosis with new evidence for hearing loss."Stover E.H., Borthwick K.J., Bavalia C., Eady N., Fritz D.M., Rungroj N., Giersch A.B.S., Morton C.C., Axon P.R., Akil I., Al-Sabban E.A., Baguley D.M., Bianca S., Bakkaloglu A., Bircan Z., Chauveau D., Clermont M.-J., Guala A. Karet F.E.J. Med. Genet. 39:796-803(2002). [3]"Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness."Karet F.E., Finberg K.E., Nelson R.D., Nayir A., Mocan H., Sanjad S.A., Rodriguez-Soriano J., Santos F., Cremers C.W.R.J., Di Pietro A., Hoffbrand B.I., Winiarski J., Bakkaloglu A., Ozen S., Dusunsel R., Goodyer P., Hulton S.A., Wu D.K. Lifton R.P.Nat. Genet. 21:84-90(1999)

Target Info

• Gene Symbol: ATP6V1B1
• Gene Full Name: ATPase H+ transporting V1 subunit B1
• Alias Symbols: ATP6B1;ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1;DRTA2;endomembrane proton pump 58 kDa subunit;H(+)-transporting two-sector ATPase, 58kD subunit;H+-ATPase beta 1 subunit;RTA1B;vacuolar proton pump 3;vacuolar proton pump subunit B 1;vacuolar proton pump, subunit 3;VATB;V-ATPase B1 subunit;V-ATPase subunit B 1;VMA2;VPP3;V-type proton ATPase subunit B, kidney isoform.
• NCBI Gene Id: 525
• Protein Name: V-type proton ATPase subunit B, kidney isoform
• Description of Target: Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
• Uniprot ID: P15313
• Protein Accession #: NP_001683
• Nucleotide Accession #: NM_001692