ATP2A1 Antibody - middle region (OASG06586)

Catalog No: OASG06586

Size:100 uL

Western Blot using HT29

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human SERCA1. Location: 520-600aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: SERCA1 Polyclonal Antibody detects endogenous levels of SERCA1 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Target Info

• Gene Symbol: ATP2A1
• Gene Full Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
• Alias Symbols: ATP2A, SERCA1
• NCBI Gene Id: 487; 11937; 116601
• Description of Target: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
• Uniprot ID: O14983, Q8R429, Q64578
• Molecular Weight: 100 kDa