Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP42722_P050
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Conjugation Options

ARP42722_P050-FITC Conjugated

ARP42722_P050-HRP Conjugated

ARP42722_P050-Biotin Conjugated

ATG4A Antibody - middle region (ARP42722_P050)

Catalog#: ARP42722_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-131432 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human ATG4A
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Complete computational species homology data Anti-ATG4A (ARP42722_P050)
Peptide Sequence Synthetic peptide located within the following region: PQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTF
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-ATG4A (ARP42722_P050) antibody is Catalog # AAP42722 (Previous Catalog # AAPP26434)
Datasheets/Manuals Printable datasheet for anti-ATG4A (ARP42722_P050) antibody
Publications

Bortnik, S; Choutka, C; Horlings, HM; Leung, S; Baker, JH; Lebovitz, C; Dragowska, WH; Go, NE; Bally, MB; Minchinton, AI; Gelmon, KA; Gorski, SM; Identification of breast cancer cell subtypes sensitive to ATG4B inhibition. 7, 66970-66988 (2016). WB, Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish 27556700

Gene Symbol ATG4A
Official Gene Full Name ATG4 autophagy related 4 homolog A (S. cerevisiae)
Alias Symbols APG4A, AUTL2
NCBI Gene Id 115201
Protein Name Cysteine protease ATG4A
Description of Target Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.
Swissprot Id Q8WYN0
Protein Accession # NP_443168
Nucleotide Accession # NM_052936
Protein Size (# AA) 398
Molecular Weight 45kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ATG4A.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ATG4A.
Protein Interactions CDKL3; GABARAPL1; GABARAPL2; ATG101; MAP1LC3B;
  1. What is the species homology for "ATG4A Antibody - middle region (ARP42722_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish".

  2. How long will it take to receive "ATG4A Antibody - middle region (ARP42722_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ATG4A Antibody - middle region (ARP42722_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ATG4A Antibody - middle region (ARP42722_P050)"?

    This target may also be called "APG4A, AUTL2" in publications.

  5. What is the shipping cost for "ATG4A Antibody - middle region (ARP42722_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ATG4A Antibody - middle region (ARP42722_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ATG4A Antibody - middle region (ARP42722_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "45kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ATG4A Antibody - middle region (ARP42722_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ATG4A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ATG4A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ATG4A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ATG4A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ATG4A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ATG4A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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