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Datasheets/Manuals | Printable datasheet for anti-ATF6 antibody - OAAB05276 |
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Predicted Species Reactivity | Human |
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Product Format | Liquid. PBS with 0.09% (W/V) sodium azide. |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Host | Rabbit |
Application | WB, IHC-P, FC |
Additional Information | Function: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. Cellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Tissue Location: Ubiquitous. |
Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | This ATF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids of human ATF6. |
Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
Predicted Homology Based on Immunogen Sequence | Mouse; Rat |
Intended Use | For research use only and not for use in diagnostic or therapeutic procedures. |
Application Info | WB: 1:16000 WB: 1:1000 IHC-P: 1:10~50 FC: 1:10~50 |
Other Applications Image 1 Data | ATF6 Antibody (Center) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Reference | Zhu,C., et.al., Mol. Cell. Biol. 17 (9), 4957-4966 (1997) Haze,K., et.al., Mol. Biol. Cell 10 (11), 3787-3799 (1999) |
Gene Symbol | ATF6 |
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Alias Symbols | ACHM7, ATF6A |
NCBI Gene Id | 22926 |
Protein Name | Cyclic AMP-dependent transcription factor ATF-6 alpha |
Description of Target | ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules. |
Uniprot ID | P18850 |
Protein Accession # | NP_031374.2 |
Molecular Weight | 74585 Da |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ATF6 Antibody - middle region (OAAB05276)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "ATF6 Antibody - middle region (OAAB05276)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "ATF6 Antibody - middle region (OAAB05276)" provided in?
This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ATF6 Antibody - middle region (OAAB05276)"?
This target may also be called "ACHM7, ATF6A" in publications.
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What is the shipping cost for "ATF6 Antibody - middle region (OAAB05276)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ATF6 Antibody - middle region (OAAB05276)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ATF6 Antibody - middle region (OAAB05276)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "74585 Da".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ATF6 Antibody - middle region (OAAB05276)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ATF6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ATF6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ATF6"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ATF6"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ATF6"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ATF6"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.