Catalog No: ARP57977_P050
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ARP57977_P050
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Datasheets/ManualsPrintable datasheet for anti-ATF5 (ARP57977_P050) antibody
Product Info
ReferenceZhou,D., (2008) J. Biol. Chem. 283 (11), 7064-7073
Publications

Wei, Y. et al. Cdc34-mediated degradation of ATF5 is blocked by cisplatin. J. Biol. Chem. 283, 18773-81 (2008). 18458088

Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human ATF5
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 93%
Peptide SequenceSynthetic peptide located within the following region: LPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRK
Concentration0.5 mg/ml
Blocking PeptideFor anti-ATF5 (ARP57977_P050) antibody is Catalog # AAP57977 (Previous Catalog # AAPP32388)
Gene SymbolATF5
Gene Full NameActivating transcription factor 5
Alias SymbolsATFX, HMFN0395
NCBI Gene Id22809
Protein NameCyclic AMP-dependent transcription factor ATF-5
Description of TargetATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma.
Uniprot IDB3KND3
Protein Accession #NP_036200
Nucleotide Accession #NM_012068
Protein Size (# AA)282
Molecular Weight31kDa
Protein InteractionsCEBPE; CEBPA; GIT2; ATXN1; EP300; CCND3; GABBR2; DISC1; GABBR1; CEBPG; CDC34; TRIB3; UBC; CD34;
  1. What is the species homology for "ATF5 Antibody - middle region (ARP57977_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish".

  2. How long will it take to receive "ATF5 Antibody - middle region (ARP57977_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ATF5 Antibody - middle region (ARP57977_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ATF5 Antibody - middle region (ARP57977_P050)"?

    This target may also be called "ATFX, HMFN0395" in publications.

  5. What is the shipping cost for "ATF5 Antibody - middle region (ARP57977_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ATF5 Antibody - middle region (ARP57977_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ATF5 Antibody - middle region (ARP57977_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "31kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ATF5 Antibody - middle region (ARP57977_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ATF5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ATF5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ATF5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ATF5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ATF5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ATF5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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