SAVE NOW with 10% off all Recombinant Antibodies Shop Now

Catalog No: ARP38067_T100
Price: $0.00
SKU
ARP38067_T100
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for anti-ATF4 (ARP38067_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Yeast
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human ATF4
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Sheep: 93%; Yeast: 82%
Peptide SequenceSynthetic peptide located within the following region: EQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLK
Concentration1.0 mg/ml
Blocking PeptideFor anti-ATF4 (ARP38067_T100) antibody is Catalog # AAP38067 (Previous Catalog # AAPP20241)
Sample Type Confirmation

ATF4 is supported by BioGPS gene expression data to be expressed in Jurkat

ReferenceLassot,I., et al., (2005) J. Biol. Chem. 280 (50), 41537-41545
Publications

Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa. PLoS One. 10, e0115723 (2015). 25695253

Gene SymbolATF4
Gene Full NameActivating transcription factor 4 (tax-responsive enhancer element B67)
Alias SymbolsCREB2, TXREB, CREB-2, TAXREB67
NCBI Gene Id468
Protein NameCyclic AMP-dependent transcription factor ATF-4
Description of TargetATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Uniprot IDP18848
Protein Accession #NP_001666
Nucleotide Accession #NM_001675
Protein Size (# AA)351
Molecular Weight39kDa
Protein InteractionsGPS2; GOLGA1; EP300; CEBPG; GOLGA8F; GOLGA8EP; GCC1; TRIB3; CCDC106; LDOC1; FBXW11; NDC80; BTRC; BFSP2; DDIT3; CREBBP; NEK6; JUN; FOS; ATF2; CEBPE; CEBPA; ATF4; ATF3; BATF2; CREBZF; BATF3; BATF; CREB3; MAFB; FOSL1; NFE2L2; NFE2; MAF; UBC; TGM2; RPS6; MAP2
  1. What is the species homology for "ATF4 Antibody - C-terminal region (ARP38067_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Yeast".

  2. How long will it take to receive "ATF4 Antibody - C-terminal region (ARP38067_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ATF4 Antibody - C-terminal region (ARP38067_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ATF4 Antibody - C-terminal region (ARP38067_T100)"?

    This target may also be called "CREB2, TXREB, CREB-2, TAXREB67" in publications.

  5. What is the shipping cost for "ATF4 Antibody - C-terminal region (ARP38067_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ATF4 Antibody - C-terminal region (ARP38067_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ATF4 Antibody - C-terminal region (ARP38067_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "39kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ATF4 Antibody - C-terminal region (ARP38067_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ATF4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ATF4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ATF4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ATF4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ATF4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ATF4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:ATF4 Antibody - C-terminal region (ARP38067_T100)
Your Rating
We found other products you might like!